XPost: alt.drugs.psychedelics

Hi there, Readers and Typers,

The OP sent this to two Linux Newsgroups where it was definitely off topic. But I think it might be ok on the two drug related newsgroups I
am sending it too.
If you thing a old lady has made a mistake then you can reply to
me on talk.politics.drugs.

bobbie sellers - a retired nurse in San Francisco

"It is by will alone I set my mind in motion.
It is by the beans of cocoa that the thoughts acquire speed,
the thighs acquire girth, the girth become a warning.
It is by theobromine alone I set my mind in motion."
--from Someone else's Dune spoof ripped to my taste.



-------- Forwarded Message --------

In recent years, there has been a resurgence of scientific and popular inte= rest in the potential use of psychedelic drugs for the treatment of depress= ion, anxiety, and post-traumatic stress. For instance, psilocybin, the acti=
ve ingredient in magic mushrooms, has shownTrusted Source promise in the tr= eatment of individuals with depression, anxiety, and substance use disorder=
s.

Naturally occurring psychedelic substances such as psilocybin extract from = magic mushrooms and mescaline have been used for their beneficial health ef= fects for thousands of years.=C2=A0

The classification of psychedelic substances such as psilocybin and LSD as = drugs of abuse without any medical use has, however, hindered research on t=
he therapeutic effects of these substances.https://buymushroomschocolatebar= s.com/product/3-5g-trippy-flip-milk-mushroom-chocolate-bars/

This has led to the adoption of a practice called microdosing,Trusted Sourc=
e, which involves the consumption of small amounts of psychedelic substance=
s that do not produce hallucinogenic effects.

Most =E2=80=98microdosers=E2=80=99 use about 10% of the regular dose of psi= locybin, equivalent to about 100-300 milligrams of dried mushrooms, between=
2-5 times a week.
=E2=80=9CThe major weakness of the study is the lack of placebo control. Th= erefore, it is unclear whether the source of these improvements is positive=
expectancy or the pharmacological action of microdosing,=E2=80=9D he
point=
ed out.
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Challenges Of Studying Psychedelics

Anecdotal reports and observational studies suggest that microdosing psyche= delics can improve cognitive function, enhance mood, and reduce anxiety and=
depressive symptoms. Most of these observational studies have used a
cross=
-sectional design, with only a few longitudinal studies comparing the effec=
ts of microdosing psilocybin with a control group over a period of time.

However, there are obstacles to conducting longitudinal studies on the effe= cts of hallucinogenic substances.

For instance, a significant number of participants in previous placebo-cont= rolled microdosing studies were able to recognize the effects of psilocybin=
during the study. In other words, participants were aware of the
treatment=
, i.e., not blinded, introducing the possibility of bias. https://buymushroomschocolatebars.com/product/cap-up-chocolate-bar/

Moreover, Trusted Sources Suggest that individuals tend to have strong expe= ctations of positive effects due to the use of psilocybin and this can resu=
lt in placebo effects.

To further characterize the potential health benefits of microdosing, the a= uthors of the present study used a naturalistic design by tracking changes =
in the mental health and mood of individuals who were already microdosing.

Specifically, the researchers compared changes in the mood, mental health, = and cognitive function of microdosers over a period of 1 month with individ= uals who were not microdosing.

Microdosers who use psilocybin often combine it with other substances such =
as the mushroom lion=E2=80=99s mane which may also possess therapeutic effe= cts. For instance, there is some evidence to suggest that lion=E2=80=99s ma=
ne mushrooms could alleviate symptomsTrusted Source of depression and mild = cognitive impairment.

Microdosers combining psilocybin and lion=E2=80=99s mane are also known to = incorporate vitamin B3, also known as niacin. Niacin is thought to improve = the absorption of psilocybin and lion=E2=80=99s mane and could potentially = enhance the effects of these mushrooms.

To better characterize the impact of these combinations on well-being, the = researchers also included participants who were microdosing psilocybin alon=
g with lion=E2=80=99s mane and niacin.

Effects of microdosing psilocybin
The present study consisted of 953 microdosers using psilocybin and 180 ind= ividuals who were not microdosing. The participants completed a series of q= uestionnaires and tasks on their mobile devices at the onset of the study a=
nd at one month after recruitment. https://buymushroomschocolatebars.com/pr= oduct/shroomies-microbites-assorted-gummies-3000mg/

These assessments included self-report questionnaires to assess mood and sy= mptoms of anxiety, depression, and stress. The researchers also assessed co= gnitive function and psychomotor ability, which refers to physical movement=
s that require cognitive processing.
These studies have generally used regular doses of psilocybin that produce = euphoric and hallucinogenic effects. However, the use of regular doses of p= silocybin can also produce unpleasant and terrifying experiences, also refe= rred to as =E2=80=9Cbad trips=E2=80=9D
The researchers found that microdosers showed greater improvements in mood = and larger reductions in symptoms of depression, anxiety, and stress over t=
he study period than non-microdosers.

These positive effects of microdosing were observed in all participants, re= gardless of whether they used psilocybin alone or a combination of either p= silocybin with lion=E2=80=99s mane, or psilocybin, lion=E2=80=99s mane, and=
niacin.

Moreover, microdosing psilocybin resulted in similar levels of improvements=
in mental health and mood across age groups, genders, and among
individual=
s who did or did not have mental health concerns.

The only exception was female microdosers who showed larger reductions in d= epressive symptoms than males. https://buymushroomschocolatebars.com/product/buy-honduras-mushroom-cubensi=
s/

In sum, the results of this study add to the current evidence on the benefi= cial effects of microdosing psilocybin on mental health and mood, including=
among individuals with mental health concerns.

Microdosing benefits: More research needed
Although the study had a large sample size, the number of individuals in va= rious subgroups according to age, gender, and substances used for microdosi=
ng was relatively small. Thus, these findings need to be replicated with la= rger sample sizes.https://buymushroomschocolatebars.com/?removed_item=3D1#q= uick-view
Dr. Bal=C3=A1zs Szigeti, a postdoctoral researcher at Imperial College Lond= on, also noted that the present study used a control group but placebo effe= cts in the microdosing group cannot be ruled out.

Dr. Szigeti explained:
=E2=80=9CThis study used a natural history control condition, meaning that = the control group did not have any treatment. This is a weak control condit= ion, although certainly better than not having any control group as in pure=
ly observational studies.=E2=80=9D https://www.google.com/search?

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