Caloric restriction causes greater longevity from turning various genes on and off, and stimulating those genes without calorie restriction causes greater lifespan, also million year lifespan endoliths lead pretty lean lives, so does restricting things
other than food cause greater lifespan? They could do human tissue culture that stays alive but see if 30%, 50%, 70% of the normal amounts of such things as oxygen, free amino acids, lipids, metalloproteins,various mineral ions causes greater tissue
culture lifespan and turns on and off completely new different longevity genes than caloric restriction, then they could give mice Other Thing mimetics and find out if they live longer even though the mice have normal amounts of oxygen, free amino acids,
lipids, metalloproteins,and mineral ions in their blood, also gene variants and SNPs about the completely new longevity genes could be numerically linked to human lifespans to find human longevity genes, they could also make completely new human
longevity genes from this as a longevity technology

When they connect the circulatory systems of a young rat and an old rat the old rat lives longer, they could do this with a variety of young rats to find out if there are any that stand out as particularly longevizing like young rats that exercise a lot
more than usual, pregnant rats, social leader (alpha) and low status rats, eunuch rats, calorie restricted rats, enriched cognitive environment rats, rats at the 99th percentile of learning ability (noting smart humans live longer),rats exposed to sex
cues (possibly odors and little rat movies of lordosis played to the young rat), or possibly bremelanotide which makes rats (or maybe mice) have sex 7 times as often), then they could find the circulating chemicals that cause even greater longevity
increase than a usual young old rat pair

Screen bremelanotide peptide and paleness producing variants to see if they make mice live longer, if so then epithalon linked to bremelanotide could be an 11 amino acid peptide, putting some D amino acids or using an enteric coating could make it an
enteric oral pill

Previously written at imaged

Notes is that at me some of my hairs turn from white back at a 3mm-24mm length of hair, suggesting they find the chemicals and genes that do that and see if they can youthify other tissues and increase longevity, along with that they could find out if
living white hairs when extract of ground up original color hair roots (follicles) is applied to them turn back to original color, at mice they could test hair follicle extract from both child mice and postpubertal but young mice, also possibly effective
would be hair follicle extract from fetal/newborn microhairs called laguno, it might be of value to test human laguno hair follicle extract (possibly from stillbirths at earlier than 7th month of pregnancy) on both mice and human white hairs, then they
find the chemicals that do the youthification

Just two genes determine if a plant is an annual or a perennial, (the internet) if those two genes (one might be Apetalla1) are turned off the plant becomes perennial, if these two genes have human homologous genes with similar sequences then they could
come up with variations on those genes, and make drugs to reduce their activity or turn them off to find out if this causes longer lifespan and find out if the chemicals, and the genes they turn on or off are longevizing, 40,000 year king's holly
versions, homologous sequences, of these genes could be utilized to find out if they cause particularly great longevity

Salicylic acid makes yeast live 400% longer, at human tissue culture they could find out if any one human tissue out of 40 or more has a strong longevity response to salicylic acid alone compared with the other types, then they could look at which genes
are activated at the most longevized tissue type compared with undrugged same tissue culture and the other non-responder tissue types, finding out what makes a longevity responder, as well as what chemicals a longevity responder makes (or decreases) and
genes it activates or decreases to live longer could be a source of new longevity drugs and longevity genetics

Do animals age at the same rate when they hibernate or estivate, the cactus mouse estivates in response to its environment, they could compare the lifespan and tissue youthfulness of cactus mice that estivate 90% of the time with cactus mice that stay
active full time in a favorable environment, they could also compare the lifespan and tissue youthfulness of calorie restricted but fully lifetime active cactus mice, the gene activation profiles and chemicals at the 90% estivating cactus mice could be
the source of new longevity drugs and chemicals and genes at humans if the estivating mice stay younger longer or also have longer lifespans, this gene and drug research could also benefit human astronauts as well

There is a wave function that describes a human and every electron and atom in them, reading that then doing a Fourier transform of it would produce a data object that an identical human could be constructed from prime number tracer quantum computer
factors emanations back to the prime number tracers move an evanescent wave microscope an atoms width to the right then record the amplitude peak, microwaves at a pair of wax prisms have about a 3mm evanescent wave pass an air gap, so if you put a yeast
cyte between the two prisms and moved the prisms and their gap say 10 or 1 or .1 nanometers a time but kept the yeast in the same location and then measured the change in the peak of the change in the evanescent wave can you image the yeast at 10
nanometer or even 1 nanometer or 10 picometer resolution for just that location in 3D space

Perhaps they could cryogenically cool the evanescent wave microscope and leave the yeast or human between the prisms warm and alive

A human head is 20ish cm wide, so an evanescent wave two prism gap would be half that at 11 cm, that corresponds to some electromagnetic frequency used to produce the evanescent wave imaging, 23 cm is an amateur radio frequency

The yeast or human between the two prisms disrupts the quantum "forbidden" zone a different amount based on how the prisms are moved, or possibly moved apart, the peak of the amplitude of that amount, accumulated, makes the image, there are drawings of
this as well as a new scientist quantum camera approach at a notebook (i will likely image)

Longevity technology

Termite queens live 50-100 years, blenderize termite queens, mass fractionate the goop, and find out which fractions, if any, fed to adult termites or larvae cause much longer lifespan, then test those chemicals (synthetic) on mice to see if they live
longer

If feeding fractionated termite queen goop to termites takes too much goop, feeding it to daphnia or fleas might work

PARP1 is described as a longevity associated gene at wikipedia and is also in plants, they could put quahog, human, white footed mouse, beaver, termite queen, lobster, and king's holly versions of PARP1 in mice and see if they live longer, if they do
then there is the advantage of finding out "what goes wrong" next, also the could put the protein parp1 codes for and inject it into mice to see if there is a longevity increase

As a topical sex pleasure cream would a GABA or other neurotransmitter antagonist cause greater pleasure from disinhibiting all the other neurons, phenibut which acts like GABA causes some penile numbness so application to the penis, clitoris and vagina
could heighten sensation, liposomes could be extra effective, there is also a GABA antagonist peptide

It is possible tiny amounts of GABA antagonist peptides as a food seasoning would amplify taste sensation at the tongue at food and candy

I may have previously written about topical GABA activators, perhaps benzodiazapenes as topical anesthetics for rashes, i do not know if there are GABA active peptides although, "glutamyl-homotaurine and GABA-glycine enhanced the potassium-stimulated
release of GABA"

Entertainment: They could take uniquely human things like shopping, typing, viewing erotic videos, brushing hair, inventing, doing advanced math, shaving, playing a musical instrument, showering, and reading and do brain scans like positron emission
tomography of fMRI then find the nonhuman mammal fMRIs, with sufficient brain localization of drugs they could harmlessly stimulate these areas on nonhuman mammals brains and then see if the nonhuman mammals liked them, as well as see if they had the
same subsequent brain activation areas as humans.Also, the drug research on nonhuman mammals could provide new ways to provide these experiences to humans without the actual activity, go shopping without going shopping and save money, experience singing
or playing a musical instrument without doing it. We would most likely like it if space aliens gave us a taste of their harmless activities.

I may have previously written about linear block rectangular magnetic fields produced with an aperture and the meissner effect

If everybody who go asked out on a romantic date asked two people to go out on a date then waves of romantic opprobrium would ripple through the globe, benefitting everybody, I like this as a social convention

Does what causrs mortality next differ between higher primate species, like do gorillas always get cardiovascular disease before cancer, and bonobos always get Alzheimer's before cardiovascular disease, genes against heart disease, cancer, or Alzheimer's
in humans might be found this way



Tire coating, get your tires painted/coated with something environmentally friendly (perhaps dissolved recycled tires) and your tires might last the life of your car, this could be applied every time you get an oil change or a lubrication job, perhaps
automatically, online it says traffic paint dries in 2 minutes with a heat source, 10 minutes without, cyanoacrylate adhesive solidifies in seconds but is crumbly, it could even come in colors

Respiratory infections were a leading cause of death among children in 2019, genetically engineering yeast to be just the right size to inhale as dust and that contain antibiotics, antivirals and mucolytics could treat this, it is even possible the yeast
could have disease preventing antigens on the outside or inside of it and do vaccinations when inhaled as a powder or, possibly, simply eaten

There is a published study that says dendrite length and number of branch points is numerically linked to higher IQ, genes that effect these and increase them are likely to be beneficial IQ heightening genes, also there are lists of proteins that effect
dendritic morphology published, with each of these proteins there is a gene that codes it, sequencing the genomes of a group of people with IQ over 180 then finding any shared trends in the genes that code for dendritic morphology amongst the IQ 180 or
higher persons then, at mice and primates,replacing the dendritic morphology genes with those numerically supported amongst the 180 IQ persons, both as separate gene-proteins as well as combined in groups, is likely to find specific gene alleles that can
be used at genetic engineering, germline modification, gene therapy, and drugs to beneficially heighten human intelligence, I favor increasing human intelligence voluntarily and would genetically increase the intelligence of my children, modifying their
genetics so their children would be of higher intelligence

Some plasma proteins cross the blood barrier more than others, taking a sample of material from plasma then finding the 99.9th percentile of proteins that pass the blood provides a list of proteins that may be ready-made protein drugs, these can also be
used as models or construction sets for completely new protein drugs, also to find proteins, possibly proteins that effect neuron morphology like dendrites that increase intelligence blenderized human brain homogenate could be injected into mice and
primates and then the 99th percentile of those that pass the blood brain barrier could be new intelligence enhancing drugs, possibly permanently increasing human intelligence, these 99th percentile btain homogenate proteins that pass the blood brain
barrier could also address voluntary personality adjustment and psychiatric applications

Dosing monkeys with stable isotope tracers from conception to one year of age, then using the easier to spot stable isotope versions at the 99th percentile of brain homogenate that passes the blood brain barrier screening to find brain proteins that pass
the blood brain barrier is another possible technique

Any source of protein can be used at the 99th percentile or 99.9th percentile of passing the blood brain barrier screening, that suggests that plants, invertebrates, endoliths with million year lifespans, and other organismal sources could be screened
this way to find ready made protein drugs as well as construction kits

There is a chance that some longevity causing protein passes the blood brain barrier, million year lifespan endoliths, 400 year quahog, 40,000 year king's holly could all be screened to find the 99th percentile of passing the blood brain barrier then
screened at mice to find out if they have cognition preserving or longevity

Online it says astrocytes next to regular endothelial cytes causes them to turn into something kind of like blood brain barrier endothelia so it may be possible to tissue culture blood brain barrier membranes to do measurement screening of proteins from
things like brain homogenates, from making this they could screen anything, not just fractionated organism homogenates, things like microfluidically produced combinatorial libraries of organic chemicals

Genetics of vitamins D production as wellness genes, beneficial gene therapy, while remaining white is there a genetics of the antidepressant effect of tanning beds as a form of antidepressant gene therapy

Snortable freeze dried adenovirus, or bacteria filled with adenovirus and a cytomembrane dissolver as a powder could be as cheap as yeast, retail 5¢ a gram, 100 mg dose .5¢, as an intelligence increasing longevity gene therapy drug available

I saw a thing with about 7 different kinds of parallel universes, one was spatial repeats, two were brand effects, two were bubble universes, so cheap ways to create "negative energy" is there a casimir effect way to create negative energy, if there is a
casimir way what volume of casimir stuff is sufficient to produce a new universe every 24 hours, can the casimir makers be angled to produce universes with particularly benevolent characteristics

They could look at human genomes and compare them to social stress resistant (SER) mice genome difference with stress susceptible mice, it is possible that just a few genes confer resistance to social stress, if they find these at humans it could be
beneficial, "control mice (CTR), stress susceptible mice (SS) and stress resilient mice (RES).","mediates depression in mice with chronic social defeat stress (CSDS)"

EEGs that cause truthfulness, playing back EEGs into the brain potentiates learning, could playing back EEGs of a person asked questions (emotionally complex or easy) who is answering truthfully cause a person to be more likely to make statements that
are true, like "did you take that candy"

St johns wort is only 2.5¢ a pill, noting weight and size differences, and that sometimes nervousness occurs at too high a dose, it is possible a "change model" where .1, .05, .25 and.5 proportions, delicious candy coated, could be at a "#" pill
container then people could customize their dose to get the greatest reduction of depression with the fewest side effects

Could topical liposomal opiate peptides relieve skin discomfort and itching from things like rashes or acne, this is likely a femtogram dose, even eating a few whole containers full would not cause intoxication, and the opiate peptide could have an
enzymatically degradable part, a stomach degradable part that would passivate it, GSK

Could putting antibodies to bacteria and festooning these with antibiotics treat antibiotic resistant organisms, enteric pills are a possibility as vaccines, insulin, and viruses can all be delivered with enteric pills

Potentiate g coupled receptors

As a new antibiotic could there be a molecule (like, but different than ethidium bromide) that intercalates (like intercalate but not DNA) bacterial surface receptors propping them open or making them go nonfunctional that is particular only to receptor
types only found on bacteria, that could weaken or terminate the bacteria, or if reception can be amplified with an intercalator, make them more susceptible to another drug (like if it were a g coupled receptors splaying or compressing the gcpr
projections would make them more sensitive to a drug or be effected with completely different drugs

At humans, nontoxic intercalators of external projections on receptors, like the finger like projections of g coupled receptors could amplify or decrease receptor response, so the nontoxic intercalators could amplify the dose effectiveness (mg per dose)
of other drugs and even create new shape based receptivity to completely new molecules, permitting new drugs wikipedia says its a flat thing (tribenzene) with a pivot so maybe a duobenzene or quadrobenzene with a pivot might do something, they could also
put a bunch of alpha helices in a container, screen a library of a bunch of different chemicals and then sort the products on shape, anything that introduces an angle or a kink in an alpha helices could be a GCPR modifying drug, imaginatively
phenylacetylene or diphenylacetylene or trip he by lac style me look kind of like ethidium, or maybe something really gentle like a benzene, maybe with a DMSO like sulfur on it in the middle of it or distal at a short few C fatty acid

I read that there are antibodies that can attach to a receptor and highly activate it, if there are antibodies that Prop open receptors as well as the glom and activate ones these could be made as antibodies from a these could activate bacterial surface
receptors found only at bacteria and confuse them or terminate them (turn water or ion pump to high on, always on), the vaccine could also make bacteria extra receptive to antibacterial drugs

Wikipedia says "Clavulanic acid is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as an antibiotic, when combined with penicillin-group antibiotics, it can overcome antibiotic resistance in
bacteria that secrete β-lactamase, which otherwise inactivates most penicillins." Would attaching clavulinic acid, or any actual antibiotic to a membrane transport moiety or peptide that only works on bacteria be much more antibiotic at much lower doses,
rather weirdly this could work with antibacterials that are not antibiotics at all like Ag-(peptide)2

Hmm can you attach a "quat" antibacterial to a cheap polymer like 10W40 motor oil that rolls up into a clump, and festoon the 10W40 with moieties or peptides that only have cytotransport at bacteria, there could also be an enzymatically dividable linker
between the "quat" and the 10W40ish polymer

When antibiotics are combined with electroporation it actually makes it so less stuff gets into bacteria (DNA), but perhaps there is a voltage and frequency that causes more stuff to get into bacteria, if there is then topical antibiotics and a handheld
electroporator could make acne or other skin infections respond to treatment sooner

MWI paint Titanium dioxide is white and produces an electrical charge when lit, they could make a paint that produces lots more MWI universes just by being on things, if you are a happy person paint your walls with it

Cars, waterparks,

MWI technology

Changing a physical switch 10,000 or more times faster than the speed of light and also creating new sizes or regions of MWI universe generation could be possible with having an electron or an atom or another observable right next to another molecule or
material that changes charge or physical shape based on spin, I have heard of spin-trap chemicals and spintronics so that should be possible; just like a regular quantum entanglement (quantum linkage) you make a spin pair, perhaps it would be beneficial
if these were atoms, electrons might work and the phrase Spin capacitor exists, once you make your entangled spin pair(or even group) you physically move them to the other side of the room or deep space, then you observe one of them and the other atom or
electron's spin is realized, it is right next to, or connected to a spintronic semiconductor which then changes its entire state, making a bit or a switch, that way you can turn things on or off 10,000 or more times faster than the speed of light; MWI
beneficial effects from changing the span and propagation and possibly area of the MWI universe produced, the only thing I remember that goes faster than light is Cerenkov radiation but there are numerous ideas online,so, is it likely or unlikely that
there is a speed of light effect at MWI universe generation, my perception is that the Schroedinger's equation people would say it just happens, if there is any localization effect from the light one then the MWI universes a Faster than light quantum
linked spin switch would have different area and immediacy, i read that thousands of atoms have been quantum entangled so if these were evenly distributed as a cloud you could fill in the entire MWI universe volume thousands of times more rapidly, if the
the thousands of spintronic switches are actuated with one observation of a happy good event then universe copies subsequent to that event are made outside the lightcone of the original event, this could place MWI universes at beyond lightcone distances
from each other, so their physics effects would not effect each other even gravity

That kind of reminds me of One Person One Planet where they make a planet, with benevolent companion robots, and then pick one person to live on it, the MWI suggests that every person is the one chosen, so each person gets their own planet, with
isolation from all the other one person one planets from using faster than light quantum entangled switches to MWI make them outside the light cone of new things on earth

I favor humans living happily one person one planet because interacting only with nonsentient robot companions removes ethical, moral, IT, some might call it IL, pattern and paranormal risks and events

Has anyone just attached the serotonin molecule to a thousand different variations on blood brain barrier passing peptides called CPPs online), giving it to 300 mice sequentially, then using computer scanned video to find out if any of them act different,
that could be a source of new antidepressant drugs, orally (possibly enteric coated or D amino acid at the peptide) available serotonin, it is possible some of these CPPs have brain localization effects which would make them different kinds of
antidepressants

CPPs linked to serotonin that have localization to brain regions or neuron types could be new nootropics

Things that fill children with happiness, services like uber might financially value giving rides to groups, it is possible parents could fund rides for teens and children old enough to go unsupervised to go as a sequentially picked up group which would
be cheaper for each individual child but be financially attractive to the transportation company, places like public parks with lots of video/audio cameras, aquatics, dance and gymnastics, enrichment schools, movies, concerts, and other activities are
possible, making an ultra safe for children driver certification would also be beneficial

Two monitor intelligence heightening software, the person has two monitors on their desk, the first that is their primary they just use as they use it, the software notices themes and introduces completely new material that makes the person more
intelligent and know more if they happen to look at the second monitor, so while I am looking at memes and reading quota on the primary monitor the other monitor has like science journal abstracts in larger print, wikihow, and maybe brain improvement
games as well as possibly wikipedia articles on the front changing the item about once each 30 seconds adding another item to a tall stack of look-at-ables like an Imgur "dump", they also quantitatively measure if people learn anything new and if their g
(like IQ) goes up, there is a certain, perhaps promoting, sense that this addresses the " what I should really be doing" and quantitatively measures that the person actually is spontaneously doing more of it

Lasers at concerts could be at harmless levels if stared directly into for the length of the concert up high, they could then be aimed at the backs of people's shirts and heads to make it so there was amazing stuff always in view, spaceships zommonig
horizontally, hearts, laserium shows, maybe even good memes

Lasers on scales that estimate your height and display BMI might be possible

Lasers or 360 degree video cameras could quantitatively measure how true all the walls, framing,and baseboards were during construction, just something you put near the center of the room, this could also be used at completed buildings to more accurately
assess their condition and value, point cloud lasers already exist so this might mostly be a software thing

Are there interferometry based VR body motion and gesture sensors, it seems like there could be

Massage chairs that could be quantitatively measured as reducing depression (paper notes) could have a mechanical horizontal travel of the kneading rollers that customizes to each persons back, sensors would locate which part of the persons back was
where, many sensor types are possible

I read that pharmaceutical companies spend a lot of money on advertising, so it is possible a new pharmacological product that is so compelling it promotes itself would be valued, one possibility are nootropic analgesics, the volume opportunities of
aspirin or aleve (naproxen) with the benefit of a nootropic, as well as the social benefits of using a nootropic, screen a library of phenylpiracetam molecularly linked to aspirin and naproxen molecular variations, as better nootropics occur, link them
to analgesics

Some Nootropics at higher than optimal dosages increase cognition but make me nervous or anxious (noopept, phenylpiracetam) delivering higher than optimal oral equivalent dosages to just particular parts of the brain could make existing and new
nootropics much more effective, they could test this with cannulas at the brains of primates, or if they respond to nootropics, farm animals, infusing nootropics just to arteries reaching particular brain areas, if they find that high doses of nootropics
above the previous optimal dose range then they could make molecules with brain localization effects perhaps keeping the extra high dose of nootropics out of the limbic system, the amygdala, and the brainstem, some possibilities are a CPP (cell
penetrating peptide), antibodies where it immunostains only at the right brain areas, or at brain cytes that are distinguishably different, efflux from cytomembrane peptides or moieties so the nootropic is ejected from places like the amygdala or limbic
system much more rapidly, the efflux moiety approach could also be used to flush the molecule out of certain kinds of neurons faster

If you put a stem cell inside an erythrocyte ghost, and decorate the outside of the erythrocyte ghost with outward facing antibodies that glom to neurons, like neurons that immunostain to be at just one area of the brain do you cause growth and increased
capability when the stem cells differentiate into new neurons at those preferred locations, you could also just put outward facing antibodies on stem cells or neuron progenitor cytes, notably just injecting stem cells into the brain is published as
neurologically beneficial

To my amazement the volume of capillaries to brain tissue in the brain is about 1/2000th the actual volume of brain tissue, "With respect to the vasculature of brain, there are > 100 billion capillaries in the human brain comprising a total length of
approximately 400 miles. Yet, the intra-endothelial volume is quite small, about 1 uL/g brain. Thus, the volume of the capillary intracellular space in brain is about 1 uL for the rat brain, and about 1 mL for the human brain. " that suggests that a
genetic change that doubles that could have cognitive or longevity effects, making mice with a simply different amount of capillaries could find genes that have cognitive and longevity benefits, also at 1/2000 the brain volume genetically doubling the
actual amount of capillaries could have cognitive benefit, these could be g (like IQ) heightening genes

I read humans have a larger number of physically smaller neurons, they could look at autopsied brains and find out if there is a neuron size IQ correlation in humans or mice, then they could repetitively breed monozygotic twin (test mouse and dissection
mouse) mice to have neurons that are 200-20% the usual size and find out if the even smaller, or larger neurons, which might even spontaneously proliferate to higher numbers making a usual volume brain, cause greater intelligence at the mice, optimizing
neuron size, largeness or smallness could be new human intelligence, like g ( g is like IQ) genes

Cold perfusion brain mapping, using a tube perfuse as many of the brain's arteries and arterioles, even capillaries if it can be accomplished with cool or cold filtered plasma, optimally from the same organism, then with MRI, behavioral tests (like blink
if they match or trace the map with your eyes or even a look at the right answer on a g (like IQ) test, or patient verbalizations of effect, this finds out which brain areas do what, also if decreasing activation, which is what cooling does, causes g (
like IQ) to increase, perhaps from decreasing (cooling) the amygdala or parts of the limbic system causes greater intelligence function, then that provides a way to increase intelligence with brain area localized drugs as well as can suggest specific
brain area size genetics as g (like IQ) increasing genes

Verbal reports of effect could find brain areas for brain surgery like, "I don't hear paranormal voices now", "the paranoia is gone, I trust you", "suddenly I feel much less depressed", "I can't feel the old injury" and then either very localized neuron
blocker drugs can be used to create a new effective custom treatment, or creates, that is finds, a site for beneficial wellness causing brain surgery

It is possible there is an area if cooled, drugged, or surgically modified decreases Alzheimer's along with those that enhance intelligence, is there an area of the brain that actually increases in size from age 49 on up? That could be a beneficial area
to cool map the effects of

I have not heard of sparse spongification forms of surgery like brain surgery, Rather than excision, halftoning with cofocal acoustics, warmth or cofocal lasers could be used to beneficially adjustably partially remove some area or organ function
permitting most of the function to continue, perhaps there are people that produce too much of some endocrine material, spongifying/halftoning endoscopically, and just possibly transdermally could be beneficial

Along with brain areas halftoning from cool plasma mapping), local body side neural areas (turning down the volume on neuropathy, could be halftones, permitting continued function or sensation while removing discomfort


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