This benefits the environment as it replaces wood materials from nature, notably wild trees, with things growable in cheap, nonsterile tanks. No, it is otherwise, the labor to harvest a tree is perhaps 2-5 minutes with automated shears and the tree has a
mass of hundreds of pounds, so the algae is not cheaper. There could be ethically sourced cellulose fiber preferences though, Ikea might prefer algae grown fibers to wild growth tree fibers.

Perhaps socially contextualized algae cellulose and tree farms could supply materials to build things from wood or algae cellulose products; my perception is that people in the US would remit a premium during 2019 AD to have higher energy efficiency and
things like solar. So, at various forms of building around the globe, renewably sourced cellulose from things like algae and tree farms could have a share, perhaps a large share, of building material and paper consumption based on consumer sociocultural
values. Then again, as far as I can figure out, algae based cellulose is not cheaper than a 2 minute snip from a tractor with shears.]]

Longevity things, the idea is that the greater the longevity the greater benefit to humans, that is people, from people who are beneficial to others; advertising longevity technologies to all humans, that is people, is optimal, yet if advertising and
communication efforts had an amount reaching less than 100% of earths population then triaging the advertising to encourage beneficial people to live longer would create measurable benefit to all the people considered as a group. The other option is
instead of triaging just figure out a form of advertising that reaches everyone on earth, effectively enough to produce longevity causing actions. I am reminded of the artificial satellite banner ad in the sky technology. It just orbits the earth,
telling people to get and take longevity drugs, on a pixel-addressable screen that communicates at all written languages.

metformin 3 times a day; if sustained plasma concentration goes with actual amount of longevity increase three times a day dosing might actually cause 1/3 more longevity effect; also is there extended release metformin. Getting that pill could work
better as well.

epitalon (20 something %)

sleep hygiene, I perceive I read that people that get 8 hours of sleep and sleep through the night live 5% or, (perhaps I misremember) 10% longer.
If I take phenylethylamine once a week, then each century of living is 52*100*20 ideas or 100,000 ish ideas and technologies that are new to me, with me preferring they be things that benefit humans, that is people. So apparently me changing my sleeping
habits could produce 50,000 to 100,000 more ideas from greater longevity.

Eununchs live, I perceive about 14 years longer, so cyproterone acetate, chemical castration could be a longevity drug.

Rapamycin, I perceive one rather lengthy treatment, caused rodenst to live 60% longer.

antiinflammatory drugs of some kind, aspirin and ibuprofen and naproxen, I do not know if COX-2 is one of them could cause weller longer lifespan, “chronic systemic inflammation becomes increasingly associated with risk of death, loss of cognitive
function and increasing dependency”

Legumes might be longevity foods, “every 20-gram increase in legume consumption produced a 7-8% reduction in mortality with or without controlling for ethnicity (p = 0.02), while “other food groups were not found to be consistently significant in
predicting survival” “Well-known legumes include alfalfa, clover, beans, peas, chickpeas, lentils, lupins, mesquite, carob, soybeans, peanuts”

A food blurb: “outcomes of more than 138,500 people ages 35 to 70 worldwide for an average of nine years”…“The people in the “healthiest” group consumed 54 percent of their diet from carbohydrates, 28 percent from fats, and 18 percent from
protein. The least healthy ate nearly 70 percent of their diet in carbs, about 18 percent from fats, and 12 percent from protein.” Cheese, avocados, vegetable oil spread that advertises as beneficial and peanut butter could possibly be beneficial




Are you aware of any drugs that when taken cause a longevity effect that occurs from a brief plasma half life, once a day dose?

Some longevity chemicals with a sustained presence at the body are, I think, supported with things like metformin circulating constantly, possibly doing some AMPK thing continuously.

Are there longevity chemicals that function as longevity increasing switches? Are there things where a dose, perhaps a high amplitude, narrow duration of effect dose causes a published longevity effect?

Two (or maybe just one) that I can think of are melatonin and the peptide epitalon. At the brain, melatonin is released as a pulsatile event, so possibly brief duration of action. I think I read melatonin make laboratory rodents live longer.

Epitalon is a 4 amino acid peptide that makes laboratory animals live longer (I perceive mid 20%) and be weller. I do not know much, but as a peptide, if you snort it, I can imagine it lasting minutes rather than hours at the circulation, so perhaps it
is a longevity turn on switch drug. Melatonin is a pineal gland secretion product, and epitalon is an engineered version of a pineal produced peptide.

It would thrill me if anyone here had ideas or knew about brief high amplitude dose longevity drugs and chemicals. What do you think some other ones are?

Senolytics also come to mind, “zap the senescent cytes with one course of treatment, live weller and longer afterwards” is kind of different than brief plasma half life longevity drugs.

Quality of life:
They could measure 12 year olds, 14 year olds, 16 year olds, 18 year olds, 22 year olds and 27 year olds to find out whate kind of lifestyle causes tha greatest quantitative happiness, well, being, quiality of romantic life, and school and life
achievement and find out which 5 or 10 teen and tween and twentysomething lifestyles, like romantic sexually active teen that does their homweork and show it to their parent nightly that goes to college and gets a scieinces or technology degree and then
seeks out employment and internships based on their interests directing them tracked from 12 to 35; also when it is better to become pregnant. The technology is to find out which of these all work together in concert, as compared with just sexually
active, just academically rigorous, and just fun single activity and perspective intensive lifestyles.
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AT the human brain there could be a 99th percentile area of reliability and a 1th percentile of reliability; such as stability over time, absence of nueronal change,what do variations on the amount of reliability do at humans. Do well humans have better
reliability even at their personal 1th percentile structures? Also,
What areas of the human brain are at 99th and 1th percentile of automatic regeneration; improving the regeneration of the 1th percentile could be a healthspan or even longevity effect. Drugs, such as new drugs that Halt or reverse decay at the 1th
percentile of brain areas resistanct to decay or messed upness could

chlorophenoxy NMN might pass the blood brain barrier causing mitochondrial improvement and better NAD things at neurons and glia. Another version might be

Chloro or other halogenated curcurmin could a a senolytic, wound healing drug that could have other benefits.

Along with the idea of a washcloth impregnated with beauty peptides, giving hundreds of beautification treatments per cloth, is the idea of a washcloth with an electret surface charge, or even piezoelectricity like PVDF that causes the chemicals in it to
be even more effective.

It is possible that electret bandages or band-aids soaked in beneficial chemicals could be quantitatively measured as being more beneficial than non-charged bandages from chemical migration.

Could chlorophenoxy moiety or other moieties that cause passage through the blood brain barrier heighten passage of beauty chemicals like peptides through the cytomembranes of the dermis making these beauty chemicals more effective? Even melatonin, which
I think I read accumulates at the nucleus, could be linked to topical beauty peptides and possibly things that modify histones, to heighten transport of beautification chemicals like peptides and poroteins to the nucleus.

A washcloth, impregnated with beauty peptides, which might actually be effective already at micrograms, such that every time you wash with it you get a coating of beauty peptides. It is noted that the wascloth gets utilized when rinsing, so the peptides
coat the face after washing is accomplished.

A scientific survey, and an engineering and medical product development application of the data from a survey, of the bacteria at normal skin, as well as particularly well, younger than actual age appearing skin, noticeably facial skin, could find a
group of bacteria, not previously known to be beneficial, that are quantifiably beneficial to the skin. Increasing the beneficial skin bacteria could be the basis of topical probiotics, prebiotics, surface topicals like things that adjust pH, or surface
hygroscopicity (things like autowetting naPCA, or alternatively surface moisture absorbing things like polyacrylimides or polyacrilic pre-gel powders). These topical, systemic (oral or other systemic drug delivery), or possibly even changing the
characteristics of the skin bacterial ecology with laser treatments, laser-resurfacing or microdermabrasion mediated bacterial ecology changers at skin to produce skin wellness and beautification from favoring some bacteria over others.

A scientific survey of well skin and skin that appears, or also is biochemically and tissue-characteristic younger than chronological age, that is used to create and engineer new products may also find non acute, non-“breakout” bacteria that are
harmful, giving the opportunity to remove, treat, or also replace these nonbeneficial bacteria with harmless or beneficial bacteria.
There is even the possibility that bacterial-species specific antibacterial chemicals like oral or topical antibiotics or different chemical topically applied medicines (possibly species specific topical Quat disinfectants, RNA drugs) could make just the
non-breakout-causing while still harmful, thus of benefit to remove preclude or kill, bacteria cease their living and activity at the skin.

Customizing skin surface with lasers or other physical treatments to create more beneficial skin bacteria ecology: changing the characteristics of the skin bacterial ecology with laser treatments, laser-resurfacing or microdermabrasion could be
structured around the number and ratio of what might be topological hills and valleys, (possibly kind of like gyrii and sulcii shapes) at the skin surface, optimally the living cytes, as well as possibly the accumulated keratin outerlayer; so, laser or
otherwise treat the keratin, and perhaps more optimally, the living dermatocyte layer, into bacterially optimal shapes, among which some possible versions are little regularly spaced ponds of depth, dendritic looking connected microchannels, or the more
high surface approach of a greater number of high plateaus which create a greater amount of high flat surface areas. The modified surface heightens and benefits more beneficial skin organism ecology, causes quantitatively measured increases in beauty,
the numbers of beneficial bacteria that have been correlated, or Koch’s postulates proved, to increase beauty, youthfulness of appearance, or also better skin healing abilitity.

It is possible that acne comes from a multi-bacteria effect, and replacing one or more of the component bacteria of the multi-bacteria effect, at the skin, with different better probiotic versions of skin bateria could reduce skin disease, preventing
reducing or even curing acne as well as causing other dermatologic nonoptimalities to cease. At a skin ecology, say one bacteria produces a proteolytic enzyme, and another different species of bacteria causes acne. Perhaps the proteolytic enzyme produced
at the first bacteria opens the skin to causing microreas of infection or just infection-prone microareas that the acne bacteria then uses, or would have used if the skin probiotic had not replaced the proteolytic version of the bacteria with a better,
nonproteolytic one, likely of the same species and nearly the same strain, as growth sites.

Another possibility, going with the perception that acne is sometimes linked to hair follicles, is that changing the bacterial species of the ecology of the hair follicle would also reduce, preclude or cure acne that has a hair follicle component; having
hair follicle sized actual areas of beneficial dermatological bacteria, like dermis probiotics, that occupy and reproduce even better with the beneficial bacteria depots creatable at hair follicles.


I perceive there might be multispecies bacterial biofilms. Are there bacterial biofilms that, even if they are without causing skin breakouts, are nonbeneficial? If there are non-breakout bacterial biofilms that should be cured or changed, then dermal
surface probiotics, skin treatments like: lasers, chemical peels, sonication, or dermabrasion, as well as topical drugs and systemic drugs, which replace some of the bacterial species at the biofilm with other species, or even a more beneficial strain of
the same species, would increase skin wellness and appearance from changing the biofilm’s effects on skin as well as changing any bacteria-bacteria interactions to be more beneficial.

It is possible that harmless viruses, notable for not being cytokilling, but still transcribed at cytes, could cause dermatocytes that get the virus to cause the production of beauty peptides and proteins, and possibly even wound-healing chemicals while
being non-cytoterminating and harmlessly infecting cytes. Notably systemic or oral as well as topical methods of this beneficial viral infection might initiate beneficial virus incorporation into skin cytes, as a topical treatment, possibly after the
dermatocytes are made more easily beneficial virus infected after a chemical peel, dermabrasion, sonic, or laser treatment. It is even possible that an physical beauty treatment like laser or chemical peel or ultrasonics, or dermabrasion, or
unintentioanl injury like an abrasion, could cause the virus to be activated notably because, and when, the dermatocytes were dividing to restore the skin.

Dermatologically beneficial virus that stays resident, and activates from normal cytodivision, a topical, systemic, or physical treatments (lasers, chemical peels, dermabrasion, sonic treatments), which possibly even uses viruses that pre-exist at the
environment, that benefit the dermis are a technology. This is a little different than gene therapy. Dermatological gene therapy also has value.

Heightening the activity and infection capability of beneficial viruses: I have not heard of any chemicals that cause normal human cytes and tissue to, alongside the application of a beneficial virus, be more easily infected. Drugs that affect IPMAT to
favor cytodivision could amplify the spread of, and proportion of infected cytes with beneficial viruses. It is possible that some chemotherapeutics like the longevity drug rapamycin increase viral infectivity.

Topical rapamycin might have a beneficial virus’ heightened infectivity effect, while also having a longevity youthful cyte and tissue producing effect from Rapamycin’s already published effects. The application of materials that heighten viral
infectivity, copy number production, and also the amount of the beneficial chemical the virus codes to produce (as well as chemicals that the virus causes the production of that occur at unmodified viruses that occur at anture, without additional genetic
coding at the virus; noting that some viruses may just be measured as having a beneficial effect, and that amplifying the proportion of cytes beneficially infected, the virus copy number, and possibly the amount of secreted proteins could be basis for
greater beneficial effectiveness). It is possible that the viruses’ dermatocyte (or other cyte and tissue) action causes greater beneficial measuable intra-cyte that is between cyte, beneficial secretion of things like proteins, peptides, or even
possibly ions as well.

application at tissues that can be reached with surface ot topical treatments; noting that published material at the scientific literature describes systemic beneficial longevity effects of rapamycin.

Another way to increase infectivity of beneficial viruses: I think I read that omitting a night of sleeping might double the infectability of the flu virus; It is possible that the chemical effects that cause that effect can be duplicated at the dermal
surface (or systemically) with a topical or systemic treatment, heightening the effectiveness of incroporation of beauty and wellness viruses into human skin cytes.

It is just possible there are amongst 2000 preexisting natural skin viruses that are already a harmless to skin cytes there could be a .5% that are actively beneficial from the effects of the viruses on beautification, preferred skin quality, such as
color, softness, and even things like controlling or blocking hair growth and fidelity of healing. These viruses could then be applied to the skin medically, it is imaginable after a laser or chemical treatment, or even, noting it is a skin-active virus,

Is there a .5% of beneficial viruses out of perhaps 2000 viruses that effect endothelial linings, that there is a bodywide epithelial and tissue membrane beneficial virus? This could be gene therapy to improve things like the GI tract lining, the
epithelial layer of the vascular system, as well as a variety of other endothelial cyte structes and tissues throughout the body. Improvements to the blood brain barrier, and the gonad-blood barrier, either increasing or decreasing the passage of
circulating chemicals, could be possible

Senolytic drugs that kill senescent cytes are published as increasing wellness and increasing longevity. Some 2019 AD senolytics are chemotherapy drugs. Some viruses are used to kill cancer cells. Finding, or genetically engineering a virus that kills
off only senescent cells is a beneficial new invention. This has the benefit of the virus being able to stay resident in the body, providing continuous senolytic action only on senescent cytes. This is a new longevity and wellness causing virus.

It is possible that systemic, or just possibly topical, chemicals or drugs that increase capillary amount, path morphology, or diameter could increase dermal tissue resilience, feel when touched, healing capability, enhancements to the chemicals and
cytostructures produced at the dermatocytes (like more collagen, or better cytoosmotics and beneficially heightened cytovolume (which might be externally perceived as the person using moisturizer, but without actually using moisturizer)) which causes
greater beauty, and may also increase things like resistance to illness, and velocitize healing. At sites where hair growth is a preference, then capillary amount, path morphology, or diameter could enhance the preferred effect on hair.

Light activated tissue growth factors as a dermal tissue and beauty increasing technology: Linking tissue growth factors to photoactivatable molecules produces light activated tissue growth factors. Noting the easy photoacessability of skin, as well as
the ability to cofocalize light, as well as the possibility that ambient daily light could turn on a photoactive chemical at the skin just from experiencing natural and ambient artificial illumination, photoactive dermatological beauty and youthfulness
drugs have technology applications. Turning things like porphrin linked growth factors or rhodopsin linked growth factors or some eentsier photoactivateable molecule linked to growth factors, to turn on and grow tissue and cause beneficial cytodivision
at the lit up area, possibly from just ambient light could possibly do things like directly opposite UV photoaging, causing sun exposure to have a net beautification and youthification at dermis.

Online material: Are there any chemicals, like proteins or chalcones, which change their shape or charge distribution when exposed to sound? If so then focused acoustics at tissue depth as well as near-surface acoustic energy transmission could activate
drugs; acoustically active drugs have numerous applications. Perhaps gentle acoustic waves at the brain could activate CNS drugs at a 1 mm voxel size.

It is even possible some beneficial cardiac medicine could be accomplished, as well as the chemotherapy agents. It is just possible that focusing acoustic waves at the placenta, while drugs quatitatively measured as being harmless or even beneficial to
the fetus, were around, that placental function, efficacy, and even shape for risk reduction could be enhanced; Sonic waves could cause a normal or undersized placenta to grow to the size most liked to fetal and baby well being, that could come from
vasodilation during the early growth phase of the placenta or the application of acoustically activateble growth factors. Also, it is possible longevity drugs could be heightened as to their localization and activitywhich It is possible a systemic dose
of tissue growth factors,

Notably, many kinds of drug localization can be technologized to benefit a pregnant woman and her fetus and baby; whether it is tissue accumulation of a chemical or drug, photoactivation, sonic activation, or even site injection, localization causes the
beneficial-to-the-mother drug to omit interacting with the fetus.

Online content: GSK: sonically activateable drugs create drug effect localization. Chalcones (zubbles might respond to sound), also stringy goopiness, biopolymers like keratin, chitin, or polyhydroxyapatite, or published as bioabsorbing, suture materials,
as well as metal microantennas like gold; the antenna fibers sized for sonic-frequency receptiveness (perhaps it is very tiny antenna sized sound frequencies like far ultrasound or something)The acoustically activateable drug antennas could be things
like hydroxypatite fibers that pick up sound, as could possibly some fibers of protein like keratin, chitin, possibly even cellulose,; perhaps a published biodegradable suture material could be microsized to pick up sounds, and have a chemical groups (
halogens? PVDF kind of effect, but at keratin or hydroxyapatite fibers, gold fibers) on it that change charge when acoustically stimulated thus changing the charge on the active drug, causing a purposed effect.

Are there any producible, or naturally occuring at tissue biopolymers, protein shapes, or just tissue morphologies that function like a telescope array? That is a grid or exapnse of 1000 eentsier proteins, occuring at a tissue, is like a radiotelescope
array, able to pick up and respond to

(emergent property: the bigger a tesselated protein grows, it could spontaneously produce, or even predictably produce something like an array telescope (radio telescope array measures big frequencies with eentsy component parts); This without one to one
photon->e- charge or

CCD (charged coupled device) like effects and various molecular charge cascades and accumulators might also be possible like: piles of e-charge ready to change and accumulate at a particular molecular direction if they get an eentsy amount of energy from
a photon or other energy source; among numerous things that could be produced wioth structures, a CCD or a current multiplying cascade could be made from layered (numerous kinds of layering: one is an amino acid linked to another, repeatedly to form a
peptide or a protein, A highly branched peptide could lay on top of itself, and when something caused the molecule to have an electrical charge shift, movement to another part of the molecule, or change, the two-treelike-brooms overlain effect causes
charge patterning at the entire polymolecule (like from nodal tesselation to gentle gradient to a different nodal looking tesselation); although modellable with quantum mechanics at molecular modelling software, this branched molecule layering effect is
something I think of as analog and having gradients, although the engineering value of a digital approach to polymer or peptide overlain trees that make charge structures (CCD, current cascade, biopolymer diode voltage doubler, biopolymer frequency
doubler)is there as well.

One topology of layered polymers like biopolymers like peptides or proteins, yet possibly completely different biopolymers, chitin (which has a nitrogen), the chitin polymer molecularly reshaped, perhaps branched, or a pendant moeity differently arranged,
differently, with the polymers or biopolymers, slightly modified to have a piezoelectric, electret, or stimulus-responsive effect (photons, acoustics, motion/bending/temperature/physical chemistry effect) that then causes charge concentration cascade, (
current cascade). 11 base pair DNA can make a diode, perhaps it is possible to make an amino acid peptide (or even just a honking big 1100 AMU molecule of some kind (1100 amu molecule is like the amu equivalent of near 14 glycines linked together) Then
with the biopolymer, peptide, or 1100 AMU (or less) biochemical, a thing made out of that can double voltage or double frequency.

Doubling voltage, current, or frequency at new chemical or a purposefully built structure possibly made with a biopolymer (or possibly a polyboron) or an organism based system gives new engineering capabilities.

Is there a way to step up a molecule’s activity, perhaps based on e- charge and HOMO, where each of 2 or three activations (beams) sequentially hops the molecules reactivity up a level. I am reminded of taking off the PO4s from ATP one by one, if you
did that and the core ws something other than adenosine, removing each PO4 might actually increase the rectivity of the core, the rest of the molecule, so each pass of activation beam would hop the chemical up a number of levels at its environment from
the beam: charge-surplus-wobbles each of the PO4s off. As sort of an extreme example: where the absorption of a beam, would pop a chelation molecule (moiety) off of an ultra-reactable, even one like CN (cyanide); if you can use localization from light or
sound to modify molecule charge, and possibly even use something like a voltage doubler amino acid structure, then you can do things where the energy would not otherwise favor the reaction, like popping off a chelation molecule.

Popping off a chelation molecule around a chemotherepeutic, cardioactive beneficial drug, drug beneficial to a fetus, longevity drug, beauty drug, or antibiotic makes a molecule that is just active at the are of localization stimulus like a cofocalized
acoustic/photonic beam. So, could having a wide field hop up the molecule 1 level, then a narrow beam, just activate the hopped up molecules at a narrow area; This remnds of engineering first and second stage rockets, it is useful technology.

If you put a frequency doubling or current doubling or voltage doubling molecule at a gaussian (or even polarized) field, does it cause the molecule at the center of the beam to have higher amounts of activation? Sort of like, if you put a spotlight
inside another spotlight (gaussian with high mid-distribution peak), and that illuminates something that doubles the photovoltaic voltage or even an acoustically responsive molecule’s charge shift/piezoelectric effect, does the comnination of those two
things give higher sptial resolution and localization of the effect? Just grabbing the precise center 10% from the middle of a gaussian distribution of a beam spreading through tissue seems possible. Then when that middle 10% reaches the frequency
doubling/current doubling biochemical (like an amino acid diode bridge moiety on a drug that becomes active when there is a change of charge or HOMO shape) does that promote activity of the drug

Another way of looking at this, is, with flashlight fingers, is there a peaked distribution of energy as compared with a uniform illumination effect? If there is could grabbing an energy profile out of that light/sound distribution’s peak create an
energy profile that could be matched to a drug? So if you beam light or sound into the body, from 1-30 cm deep, or even vertically at a human, then look for and find any existing spatial distribution peaks at the actual tissues and organs (if applicable),
then note their energy level (like joules/cm) at that localization area, then use a tuned drug that responds to just that energy (joules/cm) does the area of the drug activity have higher localization? let’s say there is 20% more (120 decijoules)
light at the middle of a gaussian beam at 2 cm deep in flashlight fingers, but most of the distribution throughout the flashlight illuminated tissue is at 100 decijoules, can you then specify a drug which only responds to 115-125 decijoules/cm energy
levels with a charge-effected drug activity? That would cause just the optimal part of the beam, even a diffuse bem, to activate the localized beneficial drug or chemical. One thing that comes to mind is that the flashlight might be 200 decijoules at the
body surface, then gradually gradient to 100 decijoules at most of the tissue, that means there are non localizion-purposed areas, say 1 cm from the surface (the localization area is the gaussian center of the beam at 120 decijoules at 2 cm deep, at some
3d area) that the drug would be unintentionally active at, unless the next technology item is made a part of the system:
Prior to the technology described immediately here, zone energy gradient would have caused drug activation at an overlayer different than the beam center energy effect, that would have caused a zone of drug activation outside the localized area. It is
possible this could be improved with cofocalization. If you are cofocalizing seven 20 decijoule beams to make a 140 decijoule focus, and the focus diffuses to produce a zone from 100 to 140 decijoules around it, if the drug is only active at 120
decijoules that makes a torus shaped drug activation zone and an absence of any near surface gradient layer with a drug activating area of the beam-passing-through-tissue gradient layer.

Can you beam some kind of radiation like EM, photons, or acoustic energy into a human where the radiation actually diffracts because of the size of the microfeatures at the human tissue? If that is possible then you could nodal concentration effects at
diffracted waves, which might be at higher resolution internal to the body than if radiation shapes were just beamed at the body, It might work with teeth or even ribs, I have no idea at soft tissue though. If there are microstructures at the body that
cause predictable internal diffraction and nodal overlap perhaps these could be used for site localization at tissues or even cytes to do medical things like activate drugs, or cause drugs to accumulate and concentrate at localized areas.

Another use of a double slit or energy/chemical binomat drugs is that you can use the bandpass of external energy activation of a drug molecule (say at 120 decijoules/cm, but not at 100 or 140 decijoules/cm).


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