Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G- quadruplexes, exosomes, and MicroRNAs

https://www.sciencedirect.com/science/article/pii/S027869152200206X

Highlights

• mRNA vaccines promote sustained synthesis of the SARS-CoV-2 spike
protein.

• The spike protein is neurotoxic, and it impairs DNA repair mechanisms.

• Suppression of type I interferon responses results in impaired innate immunity.

• The mRNA vaccines potentially cause increased risk to infectious
diseases and cancer.

• Codon optimization results in G-rich mRNA that has unpredictable complex effects.

Abstract

The mRNA SARS-CoV-2 vaccines were brought to market in response to the
public health crises of Covid-19. The utilization of mRNA vaccines in the context of infectious disease has no precedent. The many alterations in
the vaccine mRNA hide the mRNA from cellular defenses and promote a longer biological half-life and high production of spike protein. However, the
immune response to the vaccine is very different from that to a SARS-CoV-2 infection. In this paper, we present evidence that vaccination induces a profound impairment in type I interferon signaling, which has diverse
adverse consequences to human health. Immune cells that have taken up the vaccine nanoparticles release into circulation large numbers of exosomes containing spike protein along with critical microRNAs that induce a
signaling response in recipient cells at distant sites. We also identify potential profound disturbances in regulatory control of protein synthesis
and cancer surveillance. These disturbances potentially have a causal link
to neurodegenerative disease, myocarditis, immune thrombocytopenia, Bell's palsy, liver disease, impaired adaptive immunity, impaired DNA damage
response and tumorigenesis. We show evidence from the VAERS database
supporting our hypothesis. We believe a comprehensive risk/benefit
assessment of the mRNA vaccines questions them as positive contributors to public health.

Graphical abstract

https://ars.els-cdn.com/content/image/1-s2.0-S027869152200206X-ga1.jpg

…

не изглежда оптимистично.

--
«地 球 誕 生 在 牛 市 的 小 時 — Earth is born in the Bull's hour»

--- SoupGate-Win32 v1.05
* Origin: fsxNet Usenet Gateway (21:1/5)

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--- SoupGate-Win32 v1.05
* Origin: fsxNet Usenet Gateway (21:1/5)

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--- SoupGate-Win32 v1.05
* Origin: fsxNet Usenet Gateway (21:1/5)

On Tue, 19 Apr 2022 06:53:47 -0700 (PDT), Ivaylo Ivanov wrote:

Аз преди време бях пуснала подобна статия.
Ама нали съм конспиратор, сигурно никой не й обърна внимание.

Освен хора с конспиративно мислене едва ли някой друг ще обърне внимание
на статията по-горе. Не си струва дори да я коментирам.

браво бе, учения -- току-що обяви списание с импакт фактор за
конспиративно. има ли нещо между ушите или караш по добре познатия ти
почин -- „я солженицин не читал, но оссуждаю“?

--
«地 球 誕 生 在 牛 市 的 小 時 — Earth is born in the Bull's hour»

--- SoupGate-Win32 v1.05
* Origin: fsxNet Usenet Gateway (21:1/5)

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--- SoupGate-Win32 v1.05
* Origin: fsxNet Usenet Gateway (21:1/5)

On Tue, 19 Apr 2022 12:11:25 -0700 (PDT), Ivaylo Ivanov wrote:

On Tuesday, April 19, 2022 at 12:39:26 PM UTC-4, Nick wrote:

On Tue, 19 Apr 2022 06:53:47 -0700 (PDT), Ivaylo Ivanov wrote:

Аз преди време бях пуснала подобна статия.
Ама нали съм конспиратор, сигурно никой не й обърна внимание.

Освен хора с конспиративно мислене едва ли някой друг ще обърне
внимание на статията по-горе. Не си струва дори да я коментирам.

браво бе, учения -- току-що обяви списание с импакт фактор за
конспиративно. има ли нещо между ушите или караш по добре познатия ти
почин -- „я солженицин не читал, но оссуждаю“?

1) "Food and Chemical Toxicology" не е особено престижно списание.
2) Занимавам се с наука и публикувам (и чета) научни сатии редовно -
т.е. зная как "лайна" могат да се публикуват в "научно слисание"
(понякога дори най-реномираните).

ами 1) и 2) си противоречат -- щом може да се публикуват „лайна“ в
престижни списания (това между другото е друга идиотщина), какво значение
има дали food and chemical toxicology не било престижно (според теб)?

3) Прочитейки абстракта и въведението е пределно ясно, че статията е
писана от антиваксъри. Статията смърди от самото начало.

значи антиваксърите нямат право на мнение (това пък е трета идиотщина --
ваксъри <-> антиваксъри)?

4) (свързано с "3") Подхода на авторите издава погрешено разбиране на
науката ("ние знаем че ваксината е вредна и сега ще проврим всички
възможни параметри за да намерим някакво отклонение то нормата та да
докажем тезата си")

аха, значи наличието на отклонения от нормата (защото те явно са намерили
такива) не доказва ли тяхната теза? или майната им на отклоненията от
нормата, важното е да ваксинираме (останалото между редовете оставям на
теб).

За съжаление "4" е голям проблем в науката.

и какво точно е науката според теб?

не е ли точно това? хипотеза -> доказателства за нея –> теория?

ps ти да не пишеш от телефон?

--
«地 球 誕 生 在 牛 市 的 小 時 — Earth is born in the Bull's hour»

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